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Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Read available consultation questionnaire information questions about Tadalafil

Do not take Tadalafil if you have ever had an erection that lasted more than 4 hours ( was it successful? Your GP can assess this).

Talk to your doctor or pharmacist if you have any questions about the use of Tadalafil in Tadalafil’s redistributional therapy indications, or about the potential interactions with other medicines you are taking.

Tadalafil redistributional therapy indications

Tadalafil is used to treat erectile dysfunction in men. It increases the blood flow to the penis by relaxing the muscles in the prostate and mononucleosis virus in kidneys.

There are several medicines that can increase the blood flow to the penis and were used to treat Tadalafil’s distributional use.Tadalafil mononucleosis virus in kidneys

Tadalafil can increase the risk of mononucleosis (uncontrolled, high temperature, drowsy feeling, numbness, or burning) and certain infections (such as benign prostatic hyperplasia).

A mononucleosis virus study found that men who used Tadalafil had a significantly higher likelihood of developing it.

Tadalafil can also interact with other medicines such as ritonavir, which can increase the risk of infection.

There are several medications that can interact with Tadalafil including :-

• Telithromycin or quinidine

• Nitroprusside or amyl nitrite

• Isotretstan, a alpha-blocker medication

• AARI (aremitaSing), a medication used to treat pulmonary arterial hypertension and benign prostatic hyperplasia

• Telaprevir

Speak to your GP if you have any questions about how Tadalafil can be prescribed or used.

References

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.

2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/

3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf

4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36

5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs

ixieCapsittles:
  • Erectile dysfunction
  • Acne treatment [e.g. Aventica,5-alpha reductase inhibitors]
  • Urinary incontinence [e.g. The chemists suggest using tadalafil to treat urinary incontinence].
  • Vaginal infections [e.g. Utonesal, Anadin, Aventica].
  • Premature life events [e.g. cataract, Peyronie groups].
  • Skin disorders [e.g. rosacea, pustulitis].
  • Cardiac arrhythmias [e.g. left ventricular arrhythmia, ventricular tachycardia].
  • Dermatological disorders [e.g. erythema":["edema"]," ringworm].
  • Respiratory tract infections [e.g. Pneumocystis jiroveci pneumonia].
  • Bone disorders [e.g. B-18, C-815].
  • Amphetamines [e.g. diphenhydramine, paracetamol, sertraline].

** Light blue print on official NIH electronic medical write-off.

Cautions

Do not exceed the recommended dose and time.

Treatment

In non-pharmacy settings, including hospital settings, tadalafil is more commonly used as a sole treatment than as sole anti-ulcer drug. In hospital settings, including hospitalization, tadalafil is commonly used to treat patients with pulmonary arterial hypertension, or patients who have previously failed treatment with other anti-ulcer medications.

Factors that can affect the efficacy and safety of tadalafil include the patient’s age, concomitant medication, other medications being taken, and individual patient factors. For patients taking tadalafil for pulmonary arterial hypertension, the Efficacy and Eysen of Treatment (Part 1) concluded that “[w]hile tadalafil is effective in treating PAH symptoms, it has not demonstrated superiority over other non-pharmaceutical treatment options, including surgery.”

In the treatment of erectile dysfunction, the Efficacy of Treatment (Part 2) summarized the efficacy and safety of tadalafil as an EMD treatment: “[tadalafil] has been shown to be effective in the treatment of ED, with a low rate of priapism and a short duration of action. In clinical studies, priapism was reported in less than 1% of patients treated with tadalafil for 4 weeks.

Tadalafil belongs to the group of medicines called phosphodiesterase type 5 (PDE 5) inhibitors, primarily used to treat erectile dysfunction (impotence) and benign prostatic hyperplasia (BPH). Erectile dysfunction is the inability to keep a hard and erect penis suitable for sexual activity. Benign prostatic hyperplasia, also called prostate enlargement, is the non-cancerous growth of the prostate gland.

Tadalafil contains ‘Tadalafil’, which works by relaxing the blood vessels in the penis; this allows the blood to flow into the penis when the person is sexually excited. Thereby, it helps to treat erectile dysfunction. Tadalafil relaxes the bladder and prostate muscles, thereby reducing enlarged prostate symptoms such as difficulty in urination and urgent need to urinate.

You are advised to take Tadalafil for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, back pain, muscle pain, pain in the legs and arms, nasal congestion, indigestion, and facial flushing. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Tadalafil if you are taking nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension) or alpha-blockers; if you have heart problems or stroke, low blood pressure or uncontrolled high blood pressure. Tadalafil is not intended for use in women. Tadalafil may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Tadalafil should not be given to children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and the medicines you are taking to avoid unpleasant side effects.

Read the/

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Medicine NameMedicine TypeTadalafil Name
TadalafilErectile Dysfunction
Benign Prostatic Hyperplasia
You will be presented with a message that allows the doctor to determine whether or not you are suitable for taking this medicine. If you are deemed suitable for Tadalafil, your doctor will issue a prescription to your pharmacist. In most cases, Tadalafil is taken orally, with or without food, with a full glass of water. In some cases, Tadalafil may be taken in combination with other medicines such as ritonavir or saquinavir, as well as with alcohol; in these cases, your doctor may advise for you to take Tadalafil with alcohol as part of your treatment. It is important that this medicine is swallowed whole with a glass of water as it may be unsuitable for you.Side effects of Tadalafil: Vomiting, Erythema and headache. Back pain, muscle aches, flushing, upset stomach, dizziness, and headache are the most common side effects. Viagra, Cialis and Levitra are other medicines used to treat erectile dysfunction. Tadalafil works by relaxing the blood vessels in your penis; this allows the blood to flow into your penis when you are sexually excited. If you are unable to keep a penis erect, tadalafil may not be for you. Consult your doctor if you experience flushing, headache, indigestion, and muscle pain.CialisLevitraYou will be presented a message that tells the doctor about the possibility of taking this medicine. In most cases, Tadalafil is taken orally with a full glass of water.

Product Name:Tadalafil Tablets USP, 20 mg

Product Type: Tablet, Tablets

Product Form:Tablet Extended Release 24 Hour

Manufacturer:Edox Laboratories Ltd

Dosage Form:Extended Release Tablet

Strength:20 MG

Product Warning:Tadalafil is used to treat erectile dysfunction (ED), a condition that increases blood flow to the penis. Tadalafil works by increasing blood flow to the penis, helping men achieve and maintain an erection. It is important to complete the full course of treatment, even if your symptoms improve, to ensure you are getting an erection.

Generic Availability

Active Ingredient:Tadalafil 20 mg

Dosage:For Duration

Side Effects:Headache, facial flushing, back pain, muscle aches, indigestion

Warnings

If you are taking any medications,check with your doctor or pharmacist before using this product if you are pregnant, planning to become pregnant, breastfeeding or if you have kidney disease.

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References

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.

2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/

3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf

4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36

5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs

ixie Dogs, 8 cats and comparison to other PDE5 inhibitors in the treatment of pulmonary arterial hypertension. NIH Clinical Researchiol.https://www.npr.upol.edu/us/⁠GRACEYS/⁡TriMix, 3 water pills with sildenafil in order to enhance blood flow to the penis.https://www.ncbi.nlm.nih.gov/pmc/articles/N44500735/

6. Oxford Online Pharmacy. EMA%-GMP - Drug Information & Safety Standard. [Revised in December 2013] [Accessed on November 08th, 2023]https://www. OXPharmacy.org.in/getra/

Cenforce 20 20 10 mg tablet. comparison to other PDE5 inhibitors in the treatment of pulmonary arterial hypertension.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC44b4042/

7. Amgen.https://www.nberoese.com/bercollar/ apoptotic-chemokines-and-PDE5-INFants.htm

CellecteonHeliches, 90 cats and comparison to other PDE5 inhibitors in the treatment of pulmonary arterial hypertension.https://www.npr.org/lbso/LPRT00422_id6325861Coy Provides Support for Pde5 Inhibitors: A Comparative Database of Other PDE5 Inhibitors

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Cure Sphytm is a hyclate-based formulation containing hyclate monohydrate as core, magnesium stearate as protective layer, stearoyl stearate as active polymer, and titanium dioxide (E171) as the shell. Each capsule contains 40mg of stearic acid, a natural glycoside found in many plant and animal products. This multi-action feature enhances the bioavailability of PDE5 inhibitors, allowing for improved patient compliance and satisfaction. Available as tablets, capsules, gels, and blister packs.